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Revista argentina de reumatología

versão impressa ISSN 0327-4411versão On-line ISSN 2362-3675


RIVAS-VARGAS, Daniel. Diagnosis and management of the interstitial lung disease of systemic sclerosis in challenging public health conditions: Case report of the Caracas University Hospital. Rev. argent. reumatolg. [online]. 2019, vol.30, n.4, pp.18-20. ISSN 0327-4411.

A 51-year-old woman presented with swelling in both hands and a 3-months history of triphasic Raynaud phenomenon. She denied cough and dyspnea. The physical examination was notable for swollen hands, facial telangiectasia and salt and pepper lesions. She had no skin fibrosis. The determination of antinuclear antibodies and antitopoisomerase were positive. A spirometry demonstrated a forced vital capacity of 86% of the predicted. High resolution chest computed tomography revealed bilateral, basal and subpleural ground glass opacities. These findings were consistent with the diagnosis of Scleroderma-Related Interstitial Lung Disease. Moreover, due to the absence of skin fibrosis, a diagnosis of systemic sclerosis sine scleroderma was made. Infusions of endovenous cyclophosphamide were indicated at 4-week intervals, followed by oral azathioprine. This case showed that using PFT as the single screening method for SSc-ILD may cause clinicians to miss a significant number of patients and that the absence of pulmonary symptoms does not exclude lung disease in patients with normal FVC. The poor prognosis of SSc-ILD is an indication of systematic screening for early diagnosis.

Palavras-chave : Systemic Sclerosis; Lung disease; Caracas.

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