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Revista argentina de reumatología

Print version ISSN 0327-4411On-line version ISSN 2362-3675


RISCANEVO, Nadia et al. Relapsing Polychondritis as paraneoplastic phenomenon in patient with Myelodysplastic Syndrome. Rev. argent. reumatolg. [online]. 2020, vol.31, n.2, pp.42-44. ISSN 0327-4411.

Myelodysplastic syndromes are a heterogeneous group of hematological diseases, characterized by ineffective hematopoiesis with risk of progression to acute myeloid leukemia. They can be associated to autoimmune manifestations in 10-30% of patients, appearing before, during or after the diagnosis of the hematological disorder. The prevalence of relapsing polychondritis as a paraneoplastic phenomenon is 0.7-5.4%, occurring simultaneously in the majority of cases. Other associated autoimmune processes include: systemic vasculitis, seronegative polyarthritis, neutrophilic dermatosis, immunomediated cytopenias, presence of autoantibodies and cryoglobulinemia. We report the case of a 60-year-old woman, with no previous medical history, who presented with recurrent polychondritis and systemic vasculitis associated with myelodysplasia.

Keywords : Myelodysplastic syndromes; relapsing polychondritis; paraneoplastic syndromes.

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