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Revista argentina de reumatología

versión impresa ISSN 0327-4411versión On-line ISSN 2362-3675


DALPIAZ, Marina Soledad et al. Sexual dysfunction in women with systemic sclerosis. Rev. argent. reumatolg. [online]. 2022, vol.33, n.1, pp.26-34. ISSN 0327-4411.


sexual impairment (SI) is common among women with chronic diseases, including systemic sclerosis (SSc). It has been associated with characteristics such as the duration of the disease, pain, decreased functional activity, among others. To the best of our knowledge, we still do not have local data.


to evaluate the frequency of SI in women with SSc. To describe the sociodemographic characteristics, disease itself and psychological items associated with SI in women with SSc.

Materials and methods:

observational, analytical, cross-sectional study. We included women between 20 and 59 years diagnosed with SSc according to 2013 classification criteria ACR/EULAR. We excluded patients with uncontrolled chronic diseases or other autoimmune rheumatologic diseases and patients who, in the last 4 weeks, had dyspareunia or were sexually inactive due to causes not attributable to their disease. SI was assessed using the Spanish version of female sexual function index questionnaire (FSFI).


56 patients were included. 78.57% presented SI and 19.64% of them were sexually inactive patients due to the disease. Fatigue VAS (β coefficient: -0.08, CI 95%: -0.14 to -0.02; p<0.01), age (β coefficient: -0.23, CI 95%: -0.40 to -0.05; p=0.01) and fibromyalgia (β coefficient: -11.90, CI 95%: -17.98 to -5.82; p<0.01) showed significant and independent association with SI in the multivariate analysis.


SI is frequent among women with SSc, and younger patients, without fibromyalgia and with less fatigue have better sexual function.

Palabras clave : systemic scleroderma; systemic sclerosis; sexual activity; sexual behavior; physiological sexual dysfunction; sexuality; women.

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